Opportunity Information: Apply for PAR 18 346
The NINDS Research Education Programs for Residents and Fellows in Neurological Disorders and Stroke (R25 - Clinical Trial Not Allowed) is an NIH grant opportunity designed to strengthen the pipeline of physician-scientists in neurology, neurological disorders, and stroke-related fields. It uses the NIH Research Education Program (R25) mechanism, which is specifically meant to support structured research education activities that complement and enhance existing training. The central aim is workforce development: building a stronger national capacity in biomedical, behavioral, and clinical research by giving medical residents and fellows meaningful research experiences early enough in their careers to influence long-term trajectory.
The program’s emphasis is on hands-on research experiences that help clinicians develop as research scientists in areas aligned with the NINDS mission. In practical terms, the supported activities should immerse residents and fellows in research in a way that builds skills, productivity, and confidence to pursue a research career. The expectation is that these experiences are not just brief exposures, but are intentionally designed to prepare participants to be competitive for the next major step in research training and independence, particularly NIH mentored career development awards (for example, K-series awards) and, when appropriate, independent research awards. In other words, the R25 is positioned as a bridge from clinical training into a sustained physician-scientist pathway, helping participants generate the preliminary experience, mentorship, and scholarly outputs that reviewers typically expect for later career development applications.
A distinctive feature of this NINDS R25 is the requirement that program participants engage with a community beyond their home institution through an annual workshop that is specific to this funding opportunity. Participants are expected to attend and participate in this yearly meeting to present what they have done, discuss progress and future plans for transitioning to the next career stage, and network with other trainees, researchers, and leaders in relevant fields. That annual convening is meant to reinforce accountability and momentum, provide mentorship and peer learning across institutions, and help participants see and plan the concrete steps from resident or fellow to early-career investigator.
The longer-term impact NINDS is aiming for is retention and development of a stable cadre of physician-scientists who will conduct research into the mechanisms, causes (etiology), and treatment of neurological diseases. The underlying logic is that supporting clinicians during residency and fellowship, when clinical demands can crowd out research development, improves the odds that talented physicians remain in research rather than leaving the pathway. By investing in research education at this stage, NINDS is trying to strengthen both the quantity and quality of clinician investigators working on neurological disorders and stroke.
This opportunity is labeled “Clinical Trial Not Allowed,” meaning the supported research education program and the participant activities under it should not include clinical trials as defined by NIH. While participants may gain research skills and may work in clinical research environments, the FOA is not intended to support the conduct of clinical trials within the R25-supported scope. Applicants typically need to design program activities that fit clearly within non-trial research experiences and education.
Eligibility is broad across U.S.-based organizations that can run an organized research education program, including public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (both 501(c)(3) and non-501(c)(3)), for-profit organizations (other than small businesses), and small businesses, among others. The announcement explicitly highlights that a range of minority-serving institutions are eligible and encouraged, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). At the same time, the FOA is clear that non-U.S. entities cannot apply, non-U.S. components of U.S. organizations are not eligible, and foreign components are not allowed as defined by NIH policy.
From the source details provided, the administering agency is the National Institutes of Health, the activity sits within the health funding category (CFDA 93.853), and the funding instrument is a grant under an NIH discretionary program announcement (Funding Opportunity Number PAR-18-346). The original closing date listed is January 23, 2019, and the posting date information indicates it was created on November 13, 2017.Apply for PAR 18 346
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NINDS Research Education Programs for Residents and Fellows in Neurological Disorders and Stroke (R25 - Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853.
- This funding opportunity was created on 2017-11-13.
- Applicants must submit their applications by 2019-01-23. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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