Opportunity Information: Apply for RFA DA 26 024
The National Institutes of Health (NIH) is soliciting research applications for a grant opportunity titled "Engaging Loved ones in Recovery Processes to Enhance Recovery Capital and Outcomes (R61/R33 Clinical Trial Optional)" (Funding Opportunity Number: RFA-DA-26-024; CFDA: 93.279). The central aim is to close a major gap in addiction science: beyond adolescent-focused studies, there is limited evidence on how to reliably and effectively involve a persons loved ones or other key support people in ways that improve treatment navigation, engagement, and long-term recovery outcomes. This funding opportunity is designed to build that evidence base by supporting studies that strengthen the role of support persons in the recovery process.
The opportunity prioritizes pragmatic trials that can work in real-world settings and that are built for scale and sustainability. Rather than reinventing care from scratch, the focus is largely on practical adaptations to existing evidence-based practices (EBPs) and established service delivery frameworks, with the specific goal of better engaging loved ones and support persons. The underlying idea is that healthier, better-supported relationships and more informed support networks can increase "recovery capital" (the personal, social, and community resources that help someone initiate and sustain recovery), which in turn improves the chances of stable, lasting recovery.
NIH highlights several specific intervention directions that applicants can pursue. First, projects may test approaches that reduce stigma among support persons, including stigma related to addiction itself and to medications for opioid use disorder (MOUD). Second, projects may develop or refine tools and supports that help family members or other supporters navigate treatment and care options, making it easier to locate appropriate services and remain engaged over time. Third, NIH is interested in models that formally incorporate support persons into services, meaning the supporter is not just present informally but is intentionally included in the care process in a structured way. Fourth, the opportunity encourages strategies that leverage support persons as lay interventionists, where trained non-professionals in the persons support network can deliver defined supportive components that complement clinical care. Fifth, NIH is looking for interventions that directly improve the well-being and coping skills of support persons themselves, recognizing that supporters often experience stress, burnout, and health impacts that can undermine their ability to help effectively.
This is a discretionary grant mechanism using an R61/R33 structure, and it is listed as "Clinical Trial Optional," meaning applicants may propose studies with or without a clinical trial component, as long as the work fits the program goals. The R61/R33 design typically supports a phased approach where an initial stage emphasizes developing, refining, or demonstrating feasibility of the approach, followed by a second stage focused on expanded testing or evaluation once pre-specified milestones are met.
Eligibility is broad and includes many organizational types across government, academia, nonprofits, and the private sector. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled and private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations other than federally recognized tribal governments; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status; for-profit organizations (other than small businesses); and small businesses. The announcement also explicitly calls out additional eligible applicant categories, including Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; eligible federal agencies; regional organizations; U.S. territories or possessions; Indian/Native American tribal governments other than federally recognized entities; and non-U.S. (foreign) organizations.
Key administrative details provided include an original closing date of February 27, 2025, and a creation date of November 6, 2024. The award ceiling and expected number of awards are not specified in the provided source data. Overall, the opportunity is aimed at generating actionable, real-world evidence on how to better equip, involve, and support loved ones and other support persons so they can meaningfully improve care engagement, reduce stigma-related barriers, and contribute to stronger, more durable recovery outcomes.Apply for RFA DA 26 024
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Engaging Loved ones in Recovery Processes to Enhance Recovery Capital and Outcomes (R61/R33 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279.
- This funding opportunity was created on 2024-11-06.
- Applicants must submit their applications by 2025-02-27. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the title of this NIH funding opportunity?
The opportunity is titled "Engaging Loved ones in Recovery Processes to Enhance Recovery Capital and Outcomes (R61/R33 Clinical Trial Optional)."
What is the Funding Opportunity Number (FON) for this announcement?
The Funding Opportunity Number is RFA-DA-26-024.
What CFDA number is associated with this grant opportunity?
The CFDA number listed is 93.279.
What is the central aim of this funding opportunity?
The central aim is to address a major gap in addiction science by building evidence on how to reliably and effectively involve a person's loved ones or other key support people in ways that improve treatment navigation, engagement, and long-term recovery outcomes.
What problem or evidence gap is NIH trying to address?
NIH notes that, beyond adolescent-focused studies, there is limited evidence on effective ways to engage loved ones or key support persons to improve treatment navigation, engagement, and durable recovery outcomes.
What types of studies does this opportunity prioritize?
The opportunity prioritizes pragmatic trials that can work in real-world settings and are designed for scale and sustainability.
Is the focus on creating brand-new programs, or adapting existing approaches?
The focus is largely on practical adaptations to existing evidence-based practices (EBPs) and established service delivery frameworks, specifically to better engage loved ones and support persons.
What does NIH mean by "recovery capital" in this announcement?
Recovery capital refers to the personal, social, and community resources that help someone initiate and sustain recovery. The opportunity is based on the idea that stronger relationships and better-informed support networks can increase recovery capital and improve the chances of stable, lasting recovery.
Who are "loved ones" or "support persons" in the context of this grant?
They are the people in a person's support network (for example, family members or other key support people) who can play a meaningful role in treatment navigation, engagement, and ongoing recovery support.
What kinds of intervention directions does NIH specifically highlight?
NIH highlights several directions, including: (1) reducing stigma among support persons (including stigma related to addiction and to medications for opioid use disorder, MOUD); (2) developing or refining tools and supports that help supporters navigate treatment and care options; (3) formally incorporating support persons into services in a structured way; (4) leveraging support persons as trained lay interventionists to deliver defined supportive components that complement clinical care; and (5) improving the well-being and coping skills of support persons themselves.
What does "reduce stigma among support persons" include?
It includes reducing stigma related to addiction and stigma related to medications for opioid use disorder (MOUD) among the people supporting the individual in recovery.
Does the opportunity support projects that help families navigate treatment options?
Yes. NIH explicitly indicates interest in tools and supports that help family members or other supporters navigate treatment and care options, including making it easier to locate appropriate services and stay engaged over time.
What does it mean to "formally incorporate support persons into services"?
It means the supporter is not only involved informally, but is intentionally included in the care process in a structured way as part of the service model.
What does "lay interventionists" mean in this context?
It refers to trained non-professionals in the person's support network who can deliver defined supportive components that complement clinical care.
Does this opportunity include interventions focused on the support persons themselves?
Yes. NIH is interested in interventions that improve the well-being and coping skills of support persons, recognizing supporters may experience stress, burnout, and other health impacts that can reduce their ability to help effectively.
What grant mechanism is being used?
This is a discretionary grant mechanism using an R61/R33 structure.
What does the R61/R33 structure generally support?
It generally supports a phased approach: an initial stage that emphasizes developing, refining, or demonstrating feasibility, followed by a second stage that focuses on expanded testing or evaluation once pre-specified milestones are met.
Is a clinical trial required under this funding opportunity?
No. The announcement is "Clinical Trial Optional," meaning applicants may propose studies with or without a clinical trial component, as long as the work fits the program goals.
What is meant by "Clinical Trial Optional" in this announcement?
It means proposing a clinical trial is allowed but not required; projects may be clinical trial or non-clinical trial as long as they align with the goals of strengthening the role of support persons in the recovery process.
Who is eligible to apply?
Eligibility is broad and includes many organization types across government, academia, nonprofits, and the private sector, including (among others) state and local governments, special district governments, independent school districts, public and private institutions of higher education, tribal governments and tribal organizations, public housing authorities/Indian housing authorities, nonprofits with and without 501(c)(3) status, for-profit organizations (other than small businesses), and small businesses.
Are institutions serving specific populations explicitly listed as eligible?
Yes. The announcement explicitly calls out Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); and Tribally Controlled Colleges and Universities (TCCUs).
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are explicitly listed among eligible applicant categories.
Are U.S. territories or possessions eligible to apply?
Yes. U.S. territories or possessions are explicitly listed as eligible applicant categories.
Are non-U.S. (foreign) organizations eligible?
Yes. Non-U.S. (foreign) organizations are explicitly listed as eligible.
Are federal agencies eligible to apply?
Yes. Eligible federal agencies are explicitly listed among the eligible applicant categories.
Is the award ceiling provided?
No. The award ceiling is not specified in the provided source data.
Is the expected number of awards provided?
No. The expected number of awards is not specified in the provided source data.
What is the original closing date for this opportunity?
The original closing date is February 27, 2025.
What is the creation date listed for the opportunity?
The creation date is November 6, 2024.
What is the overall purpose of this opportunity in practical terms?
Overall, it aims to generate actionable, real-world evidence on how to better equip, involve, and support loved ones and other support persons so they can improve care engagement, reduce stigma-related barriers, and contribute to stronger, more durable recovery outcomes.
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