Alcohol and Other Substance Use Research Education Programs for Health Professionals (R25 Clinical Trial Not Allowed) | PAR 19 207

Opportunity Information: Apply for PAR 19 207

Alcohol and Other Substance Use Research Education Programs for Health Professionals (R25 Clinical Trial Not Allowed), Funding Opportunity Number PAR-19-207, is a National Institutes of Health (NIH) research education grant program supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug Abuse (NIDA). It uses the NIH R25 Research Education mechanism, which is meant to build and strengthen research-related knowledge and skills through structured educational activities rather than through conducting clinical trials. The central purpose of this specific opportunity is to improve how well practicing health care professionals understand and use current scientific evidence about alcohol and other substance use disorders, including the real-world clinical and public health implications of that evidence.

The overarching goal is educational: to foster a stronger understanding of biomedical, behavioral, and clinical research on alcohol and other substance use disorders and related health conditions. The program emphasizes translating scientific findings into professional learning that can shape clinical thinking and practice. The scientific areas highlighted include the neurobiology of substance use disorders, epidemiology (who is affected and how patterns change), prevention strategies, and treatment approaches. Projects are expected to focus on current and emerging knowledge, meaning applicants should design programming that keeps pace with evolving science rather than repeating basic or outdated content.

A defining feature of this FOA is its primary focus on outreach-oriented education. The intended audience is practicing health care professionals, and the supported projects should be designed to engage these professionals directly through creative educational activities. In practical terms, the strongest proposals are typically those that have a clear plan to reach clinicians and other providers where they are, remove barriers to participation, and deliver evidence-based content in accessible formats. While the FOA does not prescribe a single educational model, the emphasis is on well-structured, research-informed education that helps professionals understand advances in alcohol and substance use research and apply that understanding to prevention, identification, and treatment considerations in health settings.

The funding instrument is a grant, and the funding activity category is Education/Health. The associated CFDA numbers are 93.273 and 93.279. The opportunity lists an award ceiling of $250,000. The original closing date shown in the source information is 2022-08-10, and the opportunity was created on 2019-03-04. (Applicants should always verify whether a similar opportunity has been reissued or updated under a new notice or due date, since NIH announcements often have re-competition cycles or subsequent related FOAs.)

Eligibility is broad and includes many types of U.S.-based organizations and governmental entities. Examples include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); small businesses; public housing authorities/Indian housing authorities; and federally recognized Native American tribal governments, as well as Native American tribal organizations that are not federally recognized tribal governments. The FOA also explicitly calls out additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, U.S. territories or possessions, and Indian/Native American tribal governments other than federally recognized ones.

At the same time, there are clear restrictions related to foreign involvement. Non-domestic (non-U.S.) entities (foreign organizations) and non-domestic (non-U.S.) foreign institutions are not eligible to apply. In addition, non-domestic components of U.S. organizations are not eligible, and foreign components (as NIH defines them in the NIH Grants Policy Statement) are not allowed. In other words, applications must be firmly U.S.-based without foreign components under NIH policy for this FOA.

Finally, the label "Clinical Trial Not Allowed" is important. This means the proposed work cannot include conducting an NIH-defined clinical trial. The program is for research education and outreach, not for testing interventions through clinical trial designs. Applicants need to ensure their activities stay within education and training boundaries (for example, curriculum development, seminars, workshops, continuing education-style programming, mentoring and didactics tied to research literacy, and similar outreach education), rather than proposing prospective clinical trial research involving human participants to evaluate an intervention’s effects on health-related outcomes.

• The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Alcohol and Other Substance Use Research Education Programs for Health Professionals (R25 Clinical Trial Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273, 93.279.
• This funding opportunity was created on 2019-03-04.
• Applicants must submit their applications by 2022-08-10. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $250,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PAR 19 207

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